Exploring Data by Eye
Exploring data by eye
Targeted Protein Degradation
Utilization of the physiological proteasomal degradation process to eliminate proteins of interest. Proximity-inducing compounds such as so-called PROTACs initiate targeted degradation, e.g. via the ubiquitin-proteasome system (UPS). CelerisTx design novel proximity-inducing compounds by active machine learning approaches. https://celeristx.com/pics/
Social Immunity in Ants
Social insects are an ideal system to study the potential role of social network plasticity in disease defense. Ants are among the four species that evolved to live under obligatory eusociality; a system in which the different morphological and/or behavioral castes of a superorganism exert highly specified functions and coordinate their actions comparable to the cells of an organism’s body.
As we human beings had to experience in 2020, living under crowded conditions accelerates the spread of infectious diseases. Ants have developed fascinating collective defense strategies to overcome the threat of pathogen spread within living communities of high density and low genetic diversity.
Apoptotic cells bleb – others too.
The European moor frog
From dull brown to bright blue. Ries C., et al. (2008) Zeitschrift für Feldherpetologie, Supplement 13:127-134